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Sepsis can result in a doubling of cancer care costs


Media Release by Peter MacCallum Cancer Centre, Read the original article.

New health economics research by CEPAR researcher Dr Michelle Tew, led by the Peter MacCallum Cancer Centre and the University of Melbourne, has found sepsis can double the costs of cancer care.

Sepsis is a life-threatening illness caused by the body's response to infection, says Peter Mac's Associate Director of Health Services Research, Professor Karin Thursky, who is a senior author on the paper.

"Our best estimates are cancer patients are 10 times more likely to develop sepsis and die than non-cancer patients, due to their existing disease and the treatments they are receiving," Professor Thursky says.

As an infectious diseases physician she has pioneered programs to better recognise and manage sepsis in cancer patients.

Today's study, which was published overnight in the journal PLOS ONE, used Canadian data to track the impact of the overall use of public health services by more than 75,000 cancer patients with sepsis over five years.

The researchers could then estimate the short- and long-term costs of their care. For example, the additional cost of caring for a patient with a solid tumour who developed sepsis was over CA$60,000 over five years, and over CA$75,000 for a patient with blood cancer.

"By quantifying the economic burden of sepsis in cancer patients we have an indication of the extent of the costs associated with sepsis, and this can be used to better align resources for more efficient care of our patients," says lead author and health economist Dr Michelle Tew, a researcher at both Peter Mac and the University of Melbourne.

"We don't yet have such an incredible linked data source in Australia, but working with the Canadian team and the ICES has been a fantastic collaboration to prepare for our digital health future," Professor Thursky says.

"While it was using Canadian data, the similarities between our healthcare systems, occurrence of cancer and treatment strategies, means we believe these results are also valuable to the Australian context," says senior co-author Professor Andrew Morris, an infectious disease physician at Mount Sinai Hospital in Toronto, Canada.

"Studies like this show how important health economics research is to improve health service delivery for our patients," Professor Thursky says.

Journal/conference: PLOS ONE

Link to research (DOI): 10.1371/journal.pone.0255107

Organisation/s: Peter MacCallum Cancer Centre, The University of Melbourne

Funder: Michelle Tew is jointly supported by the NHMRC funded Centre for Research Excellence in Total Joint Replacement (1116325) and Centre for Improving Cancer Outcomes Through Enhanced Infection Services (1116876), Melbourne Research Scholarship and Australian Research Council Centre of Excellence in Population Ageing Research (CEPAR). Murray Krahn is supported by a Tier 1 Canada Research Chair in Health Technology Assessment.